no. 3-4
Dynamical Systems
Robustness in biological regulatory networks II: Application to genetic threshold Boolean random regulatory networks (getBren)
[Robustesse dans les réseaux de régulation biologique II : Application aux réseaux génétiques de régulation booléens probabilistes à Seuil]

Présenté par : the Editorial Board

Demongeot, Jacques1 ; Waku, Jules1, 2
1 AGIM CNRS/UJF 3405, université J. Fourier Grenoble I, faculté de médecine, 38700 La Tronche, France
2 LIRIMA-UMMISCO, université de Yaoundé, faculté des sciences, BP 812, Yaoundé, Cameroon
Comptes Rendus. Mathématique, Tome 350 (2012) no. 3-4, pp. 225-228.

Un exemple important de réseaux de régulation biologique est constitué par les réseaux génétiques de régulation booléens probabilistes à seuil, qui sont très utiles pour expliquer les mécanismes précis du contrôle génétique, en particulier. Cette Note montre les relations mathématiques existant entre sensibilité paramétrique de lʼentropie évolutionnaire et frustration du réseau, dans le contexte particulier de ces réseaux de régulation génétique.

An important example of biological regulatory networks is constituted by the genetic threshold Boolean random regulatory networks (getBren), which are very useful for explaining the precise mechanisms of the genetic control. This article shows the mathematical relationships between parameter sensitivity of the evolutionary entropy and network frustration in the particular context of the getBrens.

Reçu le :
Accepté le :
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DOI : 10.1016/j.crma.2012.01.019
Demongeot, Jacques 1 ; Waku, Jules 1, 2

1 AGIM CNRS/UJF 3405, université J. Fourier Grenoble I, faculté de médecine, 38700 La Tronche, France
2 LIRIMA-UMMISCO, université de Yaoundé, faculté des sciences, BP 812, Yaoundé, Cameroon 
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Demongeot, Jacques; Waku, Jules. Robustness in biological regulatory networks II: Application to genetic threshold Boolean random regulatory networks (getBren). Comptes Rendus. Mathématique, Tome 350 (2012) no. 3-4, pp. 225-228. doi : 10.1016/j.crma.2012.01.019. http://www.numdam.org/articles/10.1016/j.crma.2012.01.019/

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